Cdk5 knocking out mediated by CRISPR-Cas9 genome editing for PD-L1 attenuation and enhanced antitumor immunity

Blocking the programmed death-ligand 1 (PD-L1) on tumor cells with monoclonal antibody therapy has emerged as powerful weapon in cancer immunotherapy. However, only a minority of patients presented immune responses in clinical trials. To develop an alternative treatment method based on immune checkp...

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Ngā kaituhi matua: Huan Deng (Author), Songwei Tan (Author), Xueqin Gao (Author), Chenming Zou (Author), Chenfeng Xu (Author), Kun Tu (Author), Qingle Song (Author), Fengjuan Fan (Author), Wei Huang (Author), Zhiping Zhang (Author)
Hōputu: Pukapuka
I whakaputaina: Elsevier, 2020-02-01T00:00:00Z.
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