The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders

• Autori principali: Dasiel O. Borroto-Escuela (Autore), Karolina Wydra (Autore), Ramon Fores-Pons (Autore), Lakshmi Vasudevan (Autore), Wilber Romero-Fernandez (Autore), Małgorzata Frankowska (Autore), Luca Ferraro (Autore), Sarah Beggiato (Autore), Minerva Crespo-Ramirez (Autore), Alicia Rivera (Autore), Luisa L. Rocha (Autore), Miguel Perez de la Mora (Autore), Christophe Stove (Autore), Małgorzata Filip (Autore), Kjell Fuxe (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The widespread distribution of heteroreceptor complexes with allosteric receptor-receptor interactions in the CNS represents a novel integrative molecular mechanism in the plasma membrane of neurons and glial cells. It was proposed that they form the molecular basis for learning and short-and long-t...