CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia

Abstract Preterm infants with oxygen supplementation are at high risk for bronchopulmonary dysplasia (BPD), a neonatal chronic lung disease. Inflammation with macrophage activation is central to the pathogenesis of BPD. CXCL10, a chemotactic and pro-inflammatory chemokine, is elevated in the lungs o...

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Main Authors: Dharmesh V. Hirani (Author), Florian Thielen (Author), Siavash Mansouri (Author), Soula Danopoulos (Author), Christina Vohlen (Author), Pinar Haznedar-Karakaya (Author), Jasmine Mohr (Author), Rebecca Wilke (Author), Jaco Selle (Author), Thomas Grosch (Author), Ivana Mizik (Author), Margarete Odenthal (Author), Cristina M. Alvira (Author), Celien Kuiper-Makris (Author), Gloria S. Pryhuber (Author), Christian Pallasch (Author), S. van Koningsbruggen-Rietschel (Author), Denise Al-Alam (Author), Werner Seeger (Author), Rajkumar Savai (Author), Jörg Dötsch (Author), Miguel A. Alejandre Alcazar (Author)
Format: Book
Published: BMC, 2023-10-01T00:00:00Z.
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3rd Floor Main Library

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