CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia

• Asıl Yazarlar: Dharmesh V. Hirani (Yazar), Florian Thielen (Yazar), Siavash Mansouri (Yazar), Soula Danopoulos (Yazar), Christina Vohlen (Yazar), Pinar Haznedar-Karakaya (Yazar), Jasmine Mohr (Yazar), Rebecca Wilke (Yazar), Jaco Selle (Yazar), Thomas Grosch (Yazar), Ivana Mizik (Yazar), Margarete Odenthal (Yazar), Cristina M. Alvira (Yazar), Celien Kuiper-Makris (Yazar), Gloria S. Pryhuber (Yazar), Christian Pallasch (Yazar), S. van Koningsbruggen-Rietschel (Yazar), Denise Al-Alam (Yazar), Werner Seeger (Yazar), Rajkumar Savai (Yazar), Jörg Dötsch (Yazar), Miguel A. Alejandre Alcazar (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2023-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Preterm infants with oxygen supplementation are at high risk for bronchopulmonary dysplasia (BPD), a neonatal chronic lung disease. Inflammation with macrophage activation is central to the pathogenesis of BPD. CXCL10, a chemotactic and pro-inflammatory chemokine, is elevated in the lungs o...