Synthesis of New Thiazole-Privileged Chalcones as Tubulin Polymerization Inhibitors with Potential Anticancer Activities

Synthesis of New Thiazole-Privileged Chalcones as Tubulin Polymerization Inhibitors with Potential Anticancer Activities

A series of novel thiazole-based chalcones were evaluated for their anticancer activity as potential tubulin polymerization inhibitors. In vitro anticancer screening for the thiazole derivatives <b>2a</b>-<b>2p</b> exhibited broad-spectrum antitumor activity against various c...

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Main Authors: Hamada Hashem (Author), Abdelfattah Hassan (Author), Walid M. Abdelmagid (Author), Ahmed G. K. Habib (Author), Mohamed A. A. Abdel-Aal (Author), Ali M. Elshamsy (Author), Amr El Zawily (Author), Ibrahim Taha Radwan (Author), Stefan Bräse (Author), Ahmed S. Abdel-Samea (Author), Safwat M. Rabea (Author)
Format: Book
Published: MDPI AG, 2024-08-01T00:00:00Z.
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