PKC-Mediated Potentiation of Morphine Analgesia by St. John's Wort in Rodents and Humans

• 主要な著者: Nicoletta Galeotti (著者), Mersedeh Farzad (著者), Enrica Bianchi (著者), Carla Ghelardini (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2014-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Our purpose was to combine the use of morphine with clinically available inhibitors of protein kinase C (PKC), finally potentiating morphine analgesia in humans. Thermal tests were performed in rodents and humans previously administered with acute or chronic morphine combined or not with increasing...