PKC-Mediated Potentiation of Morphine Analgesia by St. John's Wort in Rodents and Humans

Our purpose was to combine the use of morphine with clinically available inhibitors of protein kinase C (PKC), finally potentiating morphine analgesia in humans. Thermal tests were performed in rodents and humans previously administered with acute or chronic morphine combined or not with increasing...

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Main Authors: Nicoletta Galeotti (Author), Mersedeh Farzad (Author), Enrica Bianchi (Author), Carla Ghelardini (Author)
Formato: Livro
Publicado em: Elsevier, 2014-01-01T00:00:00Z.
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