Design of novel proliposome formulation for antioxidant peptide, glutathione with enhanced oral bioavailability and stability

• Main Authors: Jong Chan Byeon (Author), Sang-Eun Lee (Author), Tae-Hyeon Kim (Author), Jung Bin Ahn (Author), Dong-Hyun Kim (Author), Jin-Seok Choi (Author), Jeong-Sook Park (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To develop proliposome formulations to improve the oral bioavailability of l-glutathione (GSH), GSH-loaded proliposomes were prepared using the granule method. Mannitol was selected as an effective excipient to achieve the desired particle size, entrapment efficiency (EE), and solubility for oral de...