Design of novel proliposome formulation for antioxidant peptide, glutathione with enhanced oral bioavailability and stability

• Główni autorzy: Jong Chan Byeon (Autor), Sang-Eun Lee (Autor), Tae-Hyeon Kim (Autor), Jung Bin Ahn (Autor), Dong-Hyun Kim (Autor), Jin-Seok Choi (Autor), Jeong-Sook Park (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

To develop proliposome formulations to improve the oral bioavailability of l-glutathione (GSH), GSH-loaded proliposomes were prepared using the granule method. Mannitol was selected as an effective excipient to achieve the desired particle size, entrapment efficiency (EE), and solubility for oral de...