Long-Acting Paliperidone Parenteral Formulations Based on Polycaprolactone Nanoparticles; the Influence of Stabilizer and Chitosan on In Vitro Release, Protein Adsorption, and Cytotoxicity

• Hoofdauteurs: Mohammed Elmowafy (Auteur), Nabil K. Alruwaili (Auteur), Khaled Shalaby (Auteur), Khalid S. Alharbi (Auteur), Waleed M. Altowayan (Auteur), Naveed Ahmad (Auteur), Ameeduzzafar Zafar (Auteur), Mohammed Elkomy (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2020-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Long-acting preparations containing the antipsychotic paliperidone for intramuscular injection has drawn considerable attention to achieve harmless long-term treatment. This study aimed to develop paliperidone loaded polycaprolactone (PCL) nanoparticles and investigate the influence of PCL/drug rati...