Long-Acting Paliperidone Parenteral Formulations Based on Polycaprolactone Nanoparticles; the Influence of Stabilizer and Chitosan on In Vitro Release, Protein Adsorption, and Cytotoxicity

• Main Authors: Mohammed Elmowafy (Author), Nabil K. Alruwaili (Author), Khaled Shalaby (Author), Khalid S. Alharbi (Author), Waleed M. Altowayan (Author), Naveed Ahmad (Author), Ameeduzzafar Zafar (Author), Mohammed Elkomy (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Long-acting preparations containing the antipsychotic paliperidone for intramuscular injection has drawn considerable attention to achieve harmless long-term treatment. This study aimed to develop paliperidone loaded polycaprolactone (PCL) nanoparticles and investigate the influence of PCL/drug rati...