Inhibition studies of bacterial α-carbonic anhydrases with phenols

• 主要な著者: Simone Giovannuzzi (著者), Chad S. Hewitt (著者), Alessio Nocentini (著者), Clemente Capasso (著者), Gabriele Costantino (著者), Daniel P. Flaherty (著者), Claudiu T. Supuran (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The α-class carbonic anhydrases (CAs, EC 4.2.1.1) from the bacterial pathogens Neisseria gonorrhoeae (NgCAα) and Vibrio cholerae (VchCAα) were investigated for their inhibition by a panel of phenols and phenolic acids. Mono-, di- and tri-substituted phenols incorporating additional hydroxyl/hydroxym...