Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

• मुख्य लेखकों: Chia-En Chang (लेखक), Chien-Ming Hsieh (लेखक), Ling-Chun Chen (लेखक), Chia-Yu Su (लेखक), Der-Zen Liu (लेखक), Hua-Jing Jhan (लेखक), Hsiu-O Ho (लेखक), Ming-Thau Sheu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The synergistic combination of docetaxel (DTX) and cisplatin (CIS) by local drug delivery with a pluronic lecithin organogel (PLO) to facilitate high drug concentrations at tumor sites and less nonspecific distribution to normal organs is thought to be beneficial in chemotherapy. In this study, usin...