Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

• Hoofdauteurs: Chia-En Chang (Auteur), Chien-Ming Hsieh (Auteur), Ling-Chun Chen (Auteur), Chia-Yu Su (Auteur), Der-Zen Liu (Auteur), Hua-Jing Jhan (Auteur), Hsiu-O Ho (Auteur), Ming-Thau Sheu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The synergistic combination of docetaxel (DTX) and cisplatin (CIS) by local drug delivery with a pluronic lecithin organogel (PLO) to facilitate high drug concentrations at tumor sites and less nonspecific distribution to normal organs is thought to be beneficial in chemotherapy. In this study, usin...