Quercetin ameliorates ulcerative colitis by restoring the balance of M2/M1 and repairing the intestinal barrier via downregulating cGAS‒STING pathway

• Egile Nagusiak: Fei Gao (Egilea), Feng Zhu (Egilea), Bo Shuai (Egilea), Meng Wu (Egilea), Chunzhu Wei (Egilea), Yuyi Yuan (Egilea), Yang Gui (Egilea), Yushi Tian (Egilea), Heng Fan (Egilea), Hui Wu (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Macrophage polarization is closely associated with the pathogenesis of ulcerative colitis (UC). Quercetin, a flavonoid, has shown promise as a treatment for inflammatory diseases, but its specific mechanism of action remains unclear. This study investigates whether quercetin can regulate intestinal...