Quercetin ameliorates ulcerative colitis by restoring the balance of M2/M1 and repairing the intestinal barrier via downregulating cGAS‒STING pathway

• Main Authors: Fei Gao (Author), Feng Zhu (Author), Bo Shuai (Author), Meng Wu (Author), Chunzhu Wei (Author), Yuyi Yuan (Author), Yang Gui (Author), Yushi Tian (Author), Heng Fan (Author), Hui Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophage polarization is closely associated with the pathogenesis of ulcerative colitis (UC). Quercetin, a flavonoid, has shown promise as a treatment for inflammatory diseases, but its specific mechanism of action remains unclear. This study investigates whether quercetin can regulate intestinal...