Bilirubin inhibits neointima formation and vascular smooth muscle cell proliferation and migration

• Glavni autori: Kelly J. Peyton (Autor), Ahmad R. Shebib (Autor), Mohammad A. Azam (Autor), Xiao-ming eLiu (Autor), David A. Tulis (Autor), William eDurante (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2012-03-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Bilirubin is a heme metabolite generated by the concerted action of the enzymes heme oxygenase and biliverdin reductase. Although long considered a toxic byproduct of heme catabolism, recent preclinical and clinical studies indicate the bilirubin exerts beneficial effects in the circulation. In the...