Drug-Induced Reorganisation of Lipid Metabolism Limits the Therapeutic Efficacy of Ponatinib in Glioma Stem Cells

Drug-Induced Reorganisation of Lipid Metabolism Limits the Therapeutic Efficacy of Ponatinib in Glioma Stem Cells

The standard of care for glioblastoma (GBM) involves surgery followed by adjuvant radio- and chemotherapy, but often within months, patients relapse, and this has been linked to glioma stem cells (GSCs), self-renewing cells with increased therapy resistance. The identification of the epidermal growt...

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Main Authors: Paula Aldaz (Author), Ana Olias-Arjona (Author), Irene Lasheras-Otero (Author), Karina Ausin (Author), Marta Redondo-Muñoz (Author), Claudia Wellbrock (Author), Enrique Santamaria (Author), Joaquin Fernandez-Irigoyen (Author), Imanol Arozarena (Author)
Format: Book
Published: MDPI AG, 2024-05-01T00:00:00Z.
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