Drug-Induced Reorganisation of Lipid Metabolism Limits the Therapeutic Efficacy of Ponatinib in Glioma Stem Cells

• প্রধান লেখক: Paula Aldaz (লেখক), Ana Olias-Arjona (লেখক), Irene Lasheras-Otero (লেখক), Karina Ausin (লেখক), Marta Redondo-Muñoz (লেখক), Claudia Wellbrock (লেখক), Enrique Santamaria (লেখক), Joaquin Fernandez-Irigoyen (লেখক), Imanol Arozarena (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2024-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The standard of care for glioblastoma (GBM) involves surgery followed by adjuvant radio- and chemotherapy, but often within months, patients relapse, and this has been linked to glioma stem cells (GSCs), self-renewing cells with increased therapy resistance. The identification of the epidermal growt...