Oral Formulation Based on Irbesartan Nanocrystals Improve Drug Solubility, Absorbability, and Efficacy

• Päätekijät: Noriaki Nagai (Tekijä), Fumihiko Ogata (Tekijä), Ayari Ike (Tekijä), Yurisa Shimomae (Tekijä), Hanano Osako (Tekijä), Yosuke Nakazawa (Tekijä), Naoki Yamamoto (Tekijä), Naohito Kawasaki (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

We previously reported that the bioavailability (BA) of irbesartan (IRB), a BSC class II drug, was improved by preparing nanocrystalline suspensions. However, nanocrystalline suspensions have chemical and physical instabilities and must be converted into tablets through drying approaches in order to...