Altered Immunoregulation in Rheumatoid Arthritis: The Role of Regulatory T Cells and Proinflammatory Th17 Cells and Therapeutic Implications
In recent years several studies investigated the role of T lymphocyte subpopulations in the pathogenesis of rheumatoid arthritis (RA). Pathogenic Th17 cells mediate pannus growth, osteoclastogenesis, and synovial neoangiogenesis; hence they are key players in the development of the disease. On the o...
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Main Authors: | Alessia Alunno (Author), Mirko Manetti (Author), Sara Caterbi (Author), Lidia Ibba-Manneschi (Author), Onelia Bistoni (Author), Elena Bartoloni (Author), Valentina Valentini (Author), Riccardo Terenzi (Author), Roberto Gerli (Author) |
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Format: | Book |
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Hindawi Limited,
2015-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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