New lathyrane diterpenoid hybrids have anti-inflammatory activity through the NF-κB signaling pathway and autophagy

• मुख्य लेखकों: Wang Wang (लेखक), Liangliang Xiong (लेखक), Yanli Wu (लेखक), Yirong Zhou (लेखक), Yutong Li (लेखक), Mengzhu Zheng (लेखक), Zhuorui Song (लेखक), Dejuan Sun (लेखक), Lixia Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Compuscript Ltd, 2022-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In our ongoing work on the identification of potent anti-inflammatory agents, we designed and synthesized three series of lathyrane diterpenoid hybrids in which the lathyrane diterpenoid skeleton was hybridized with other anti-inflammatory pharmacophores. Unexpectedly, lathyrane diterpenoid/3-hydrox...