Rapid identification and isolation of neuraminidase inhibitors from mockstrawberry (Duchesnea indica Andr.) based on ligand fishing combined with HR-ESI-Q-TOF-MS

• Váldodahkkit: Sifan Luo (Dahkki), Linbo Guo (Dahkki), Caimin Sheng (Dahkki), Yumei Zhao (Dahkki), Ling Chen (Dahkki), Chufang Li (Dahkki), Zhengjin Jiang (Dahkki), Haiyan Tian (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2020-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Neuraminidase inhibitors (NAIs) are the mainstay antiviral drugs against influenza infection. In this study, a ligand fishing protocol was developed to screen NAIs using neuraminidase immobilized magnetic beads (NA-MB). After verifying the feasibility of NA-MB with an artificial mixture including NA...