Teriflunomide preserves peripheral nerve mitochondria from oxidative stress-mediated alterations

• 主要な著者: Bimala Malla (著者), Samuel Cotten (著者), Rebecca Ulshoefer (著者), Friedemann Paul (著者), Anja E. Hauser (著者), Raluca Niesner (著者), Helena Bros (著者), Carmen Infante-Duarte (著者)
• フォーマット: 図書
• 出版事項: SAGE Publishing, 2020-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Mitochondrial dysfunction is a common pathological hallmark in various inflammatory and degenerative diseases of the central nervous system, including multiple sclerosis (MS). We previously showed that oxidative stress alters axonal mitochondria, limiting their transport and inducing conformational...