A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors

• Hoofdauteurs: Anjali Bajpai (Auteur), Taushif Ahmad Quazi (Auteur), Hong-Wen Tang (Auteur), Nishat Manzar (Auteur), Virender Singh (Auteur), Ashwani Thakur (Auteur), Bushra Ateeq (Auteur), Norbert Perrimon (Auteur), Pradip Sinha (Auteur)
• Formaat: Boek
• Gepubliceerd in: The Company of Biologists, 2020-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Peptide therapeutics, unlike small-molecule drugs, display crucial advantages of target specificity and the ability to block large interacting interfaces, such as those of transcription factors. The transcription co-factor of the Hippo pathway, YAP/Yorkie (Yki), has been implicated in many cancers,...