A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors

• Main Authors: Anjali Bajpai (Author), Taushif Ahmad Quazi (Author), Hong-Wen Tang (Author), Nishat Manzar (Author), Virender Singh (Author), Ashwani Thakur (Author), Bushra Ateeq (Author), Norbert Perrimon (Author), Pradip Sinha (Author)
• Format: Knjiga
• Izdano: The Company of Biologists, 2020-07-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Peptide therapeutics, unlike small-molecule drugs, display crucial advantages of target specificity and the ability to block large interacting interfaces, such as those of transcription factors. The transcription co-factor of the Hippo pathway, YAP/Yorkie (Yki), has been implicated in many cancers,...