A case report of a prolonged decrease in tacrolimus clearance due to co-administration of nirmatrelvir/ritonavir in a lung transplant recipient receiving itraconazole prophylaxis

• Päätekijät: Ayumi Tsuzawa (Tekijä), Yoshiki Katada (Tekijä), Keisuke Umemura (Tekijä), Mitsuhiro Sugimoto (Tekijä), Asami Nishikawa (Tekijä), Yu-ki Sato (Tekijä), Yuko Yoshida (Tekijä), Noriaki Kitada (Tekijä), Atsushi Yonezawa (Tekijä), Daisuke Nakajima (Tekijä), Hiroshi Date (Tekijä), Tomohiro Terada (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2023-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Drug-drug interaction management is complex. Nirmatrelvir/ritonavir is a potent cytochrome P450 (CYP) 3A inhibitor and influences pharmacokinetics of co-administered drugs. Although there are several reports about drug-drug interactions of nirmatrelvir/ritonavir, an influence of...