Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia

• Hlavní autoři: Manivannan Subramanian (Autor), Suman Kumar Metya (Autor), Sufia Sadaf (Autor), Satish Kumar (Autor), Dominik Schwudke (Autor), Gaiti Hasan (Autor)
• Médium: Kniha
• Vydáno: The Company of Biologists, 2013-05-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

SUMMARY Obesity is a complex metabolic disorder that often manifests with a strong genetic component in humans. However, the genetic basis for obesity and the accompanying metabolic syndrome is poorly defined. At a metabolic level, obesity arises from an imbalance between the nutritional intake and...