Altered lipid homeostasis in Drosophila InsP3 receptor mutants leads to obesity and hyperphagia

• Main Authors: Manivannan Subramanian (Author), Suman Kumar Metya (Author), Sufia Sadaf (Author), Satish Kumar (Author), Dominik Schwudke (Author), Gaiti Hasan (Author)
• Format: Book
• Published: The Company of Biologists, 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Obesity is a complex metabolic disorder that often manifests with a strong genetic component in humans. However, the genetic basis for obesity and the accompanying metabolic syndrome is poorly defined. At a metabolic level, obesity arises from an imbalance between the nutritional intake and...