Distinct anti-proliferative effects of herbal melanin on human acute monocytic leukemia THP-1 cells and embryonic kidney HEK293 cells

• Váldodahkkit: Adila El-Obeid (Dahkki), Hala Alajmi (Dahkki), Mashael Harbi (Dahkki), Wesam Bin Yahya (Dahkki), Hamad Al-Eidi (Dahkki), Monira Alaujan (Dahkki), Adil Haseeb (Dahkki), Thadeo Trivilegio (Dahkki), Alshaimaa Alhallaj (Dahkki), Saleh Alghamdi (Dahkki), Abdul-Wali Ajlouni (Dahkki), Sabine Matou-Nasri (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: BMC, 2020-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Background Herbal melanin (HM) is a dark pigment extracted from the seed coat of Nigella sativa L. and known to exert biological effects via toll-like receptor 4 (TLR4). Recently, TLR4 was described as involved in natural programmed cell death (apoptosis). Tumor and embryonic cells are used...