Tat-functionalized Ag-Fe3O4 nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery

• Glavni autori: Ergang Liu (Autor), Meng Zhang (Autor), Hui Cui (Autor), Junbo Gong (Autor), Yongzhuo Huang (Autor), Jianxin Wang (Autor), Yanna Cui (Autor), Weibing Dong (Autor), Lu Sun (Autor), Huining He (Autor), Victor C. Yang (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2018-10-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

In this paper, we prepared a dual functional system based on dextrin-coated silver nanoparticles which were further attached with iron oxide nanoparticles and cell penetrating peptide (Tat), producing Tat-modified Ag-Fe3O4 nanocomposites (Tat-FeAgNPs). To load drugs, an -SH containing linker, 3-merc...