Pharmacogenomics of celiprolol - evidence for a role of P‐glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics

• Главные авторы: Päivi Hirvensalo (Автор), Aleksi Tornio (Автор), Tuija Tapaninen (Автор), Maria Paile‐Hyvärinen (Автор), Mikko Neuvonen (Автор), Janne T. Backman (Автор), Mikko Niemi (Автор)
• Формат: ‌
• Опубликовано: Wiley, 2022-02-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract The aim of this study was to search for associations of genetic variants with celiprolol pharmacokinetics in a large set of pharmacokinetic genes, and, more specifically, in a set of previously identified candidate genes ABCB1, SLCO1A2, and SLCO2B1. To this end, we determined celiprolol sin...