Pharmacogenomics of celiprolol - evidence for a role of P‐glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics

• Main Authors: Päivi Hirvensalo (Author), Aleksi Tornio (Author), Tuija Tapaninen (Author), Maria Paile‐Hyvärinen (Author), Mikko Neuvonen (Author), Janne T. Backman (Author), Mikko Niemi (Author)
• Format: Book
• Published: Wiley, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The aim of this study was to search for associations of genetic variants with celiprolol pharmacokinetics in a large set of pharmacokinetic genes, and, more specifically, in a set of previously identified candidate genes ABCB1, SLCO1A2, and SLCO2B1. To this end, we determined celiprolol sin...