Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: Desensitization of N-Methyl-D-aspartate Receptor Channels

• Hauptverfasser: Noritaka Nakamichi (Verfasst von), Yukio Yoneda (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2005-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

N-Methyl-D-aspartate (NMDA) receptors are a principal subtype of excitatory ligand-gated ion channels with crucial roles in a variety of physiological and pathological processes in the mammalian central nervous system (CNS). In contrast to synaptic non-NMDA receptors that rapidly internalize, synapt...