Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: Desensitization of N-Methyl-D-aspartate Receptor Channels

• Auteurs principaux: Noritaka Nakamichi (Auteur), Yukio Yoneda (Auteur)
• Format: Livre
• Publié: Elsevier, 2005-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

N-Methyl-D-aspartate (NMDA) receptors are a principal subtype of excitatory ligand-gated ion channels with crucial roles in a variety of physiological and pathological processes in the mammalian central nervous system (CNS). In contrast to synaptic non-NMDA receptors that rapidly internalize, synapt...