Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity

• Autores principales: Matteo Tardelli (Autor), Karina Zeyda (Autor), Veronica Moreno-Viedma (Autor), Bettina Wanko (Autor), Nicole G. Grün (Autor), Günther Staffler (Autor), Maximilian Zeyda (Autor), Thomas M. Stulnig (Autor)
• Formato: Libro
• Publicado: Elsevier, 2016-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Objective: Recent findings point towards an important role of local macrophage proliferation also in obesity-induced adipose tissue inflammation that underlies insulin resistance and type 2 diabetes. Osteopontin (OPN) is an inflammatory cytokine highly upregulated in adipose tissue (AT) of obese and...