DoE-Assisted Development of a Novel Glycosaminoglycan-Based Injectable Formulation for Viscosupplementation

• Главные авторы: Marta Cicognani (Автор), Silvia Rossi (Автор), Gabriele Vecchi (Автор), Andrea Maria Giori (Автор), Franca Ferrari (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2020-07-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

The aim of the present work was the development of a novel glycosaminoglycan (GAG)-based injectable formulation intended for intra-articular administration that should best mimic the healthy synovial fluid. Hyaluronic acid (HA) was chosen among GAG polymers, since it is the most abundant component o...