DoE-Assisted Development of a Novel Glycosaminoglycan-Based Injectable Formulation for Viscosupplementation

• Hauptverfasser: Marta Cicognani (Verfasst von), Silvia Rossi (Verfasst von), Gabriele Vecchi (Verfasst von), Andrea Maria Giori (Verfasst von), Franca Ferrari (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2020-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The aim of the present work was the development of a novel glycosaminoglycan (GAG)-based injectable formulation intended for intra-articular administration that should best mimic the healthy synovial fluid. Hyaluronic acid (HA) was chosen among GAG polymers, since it is the most abundant component o...