Genetic analysis of Wnt/PCP genes in neural tube defects
Abstract Background Mouse homozygous mutants in Wnt/planar cell polarity (PCP) pathway genes have been shown to cause neural tube defects (NTDs) through the disruption of normal morphogenetic processes critical to neural tube closure (NTC). Knockout mice that are heterozygotes of single PCP genes li...
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2018-04-01T00:00:00Z.
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