Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis

• 主要な著者: Chengniu Wang (著者), Weizhen Wang (著者), Jin Dong (著者), Xiaoran Li (著者), Taowen Ye (著者), Fanshuo Zeng (著者), Mingyu Jiang (著者), Jianwu Shi (著者), Xiaorong Wang (著者), Lei Zhang (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

IntroductionFerroptosis, induced by iron overload and an imbalance in redox homeostasis, promotes the generation of reactive oxygen species (ROS), leading to iron-dependent lipid peroxides (LPO) and oxidative stress. Lipid peroxidation induced by reactive oxygen species is essential for the progress...