RNA-binding protein YBX3 promotes PPARγ-SLC3A2 mediated BCAA metabolism fueling brown adipogenesis and thermogenesis

• Príomhchruthaitheoirí: Lin-Yun Chen (Údar), Li-Wen Wang (Údar), Jie Wen (Údar), Jing-Dong Cao (Údar), Rui Zhou (Údar), Jin-Lin Yang (Údar), Ye Xiao (Údar), Tian Su (Údar), Yan Huang (Údar), Qi Guo (Údar), Hai-Yan Zhou (Údar), Xiang-Hang Luo (Údar), Xu Feng (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2024-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Objective: Activating brown adipose tissue (BAT) thermogenesis is a promising approach to combat obesity and metabolic disorders. The post-transcriptional regulation of BAT thermogenesis mediated by RNA-binding proteins (RBPs) is still not fully understood. This study explores the physiological role...