RNA-binding protein YBX3 promotes PPARγ-SLC3A2 mediated BCAA metabolism fueling brown adipogenesis and thermogenesis

• Main Authors: Lin-Yun Chen (Author), Li-Wen Wang (Author), Jie Wen (Author), Jing-Dong Cao (Author), Rui Zhou (Author), Jin-Lin Yang (Author), Ye Xiao (Author), Tian Su (Author), Yan Huang (Author), Qi Guo (Author), Hai-Yan Zhou (Author), Xiang-Hang Luo (Author), Xu Feng (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Activating brown adipose tissue (BAT) thermogenesis is a promising approach to combat obesity and metabolic disorders. The post-transcriptional regulation of BAT thermogenesis mediated by RNA-binding proteins (RBPs) is still not fully understood. This study explores the physiological role...