Mycolactone gene expression is controlled by strong SigA-like promoters with utility in studies of Mycobacterium ulcerans and buruli ulcer.

• প্রধান লেখক: Nicholas J Tobias (লেখক), Torsten Seemann (লেখক), Sacha J Pidot (লেখক), Jessica L Porter (লেখক), Laurent Marsollier (লেখক), Estelle Marion (লেখক), Franck Letournel (লেখক), Tasnim Zakir (লেখক), Joseph Azuolas (লেখক), John R Wallace (লেখক), Hui Hong (লেখক), John K Davies (লেখক), Benjamin P Howden (লেখক), Paul D R Johnson (লেখক), Grant A Jenkin (লেখক), Timothy P Stinear (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Mycolactone A/B is a lipophilic macrocyclic polyketide that is the primary virulence factor produced by Mycobacterium ulcerans, a human pathogen and the causative agent of Buruli ulcer. In M. ulcerans strain Agy99 the mycolactone polyketide synthase (PKS) locus spans a 120 kb region of a 174 kb mega...