Single‐dose of LC51‐0255, a selective S1P1 receptor modulator, showed dose‐dependent and reversible reduction of absolute lymphocyte count in humans

Abstract Reducing the peripheral absolute lymphocyte count (ALC) is a promising therapeutic approach in treating autoimmune diseases. LC51‐0255 is a sphingosine‐1‐phosphate 1 receptor modulator, which is known to decrease the peripheral ALC. We aimed to assess the pharmacokinetics (PKs), pharmacodyn...

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Egile Nagusiak: Sang Won Lee (Egilea), Inyoung Hwang (Egilea), Jaeseong Oh (Egilea), SeungHwan Lee (Egilea), In‐Jin Jang (Egilea), Kyung‐Sang Yu (Egilea)
Formatua: Liburua
Argitaratua: Wiley, 2022-04-01T00:00:00Z.
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