Phosphonamidates are the first phosphorus-based zinc binding motif to show inhibition of β-class carbonic anhydrases from bacteria, fungi, and protozoa

A primary strategy to combat antimicrobial resistance is the identification of novel therapeutic targets and anti-infectives with alternative mechanisms of action. The inhibition of the metalloenzymes carbonic anhydrases (CAs, EC 4.2.1.1) from pathogens (bacteria, fungi, and protozoa) was shown to p...

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Main Authors: Siham A. Alissa (Author), Hanan A. Alghulikah (Author), Zeid A. Alothman (Author), Sameh M. Osman (Author), Sonia Del Prete (Author), Clemente Capasso (Author), Alessio Nocentini (Author), Claudiu T. Supuran (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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