Effects of chronic high fat diet on mediobasal hypothalamic satiety neuron function in POMC-Cre mice

• Auteurs principaux: Özge Başer (Auteur), Yavuz Yavuz (Auteur), Deniz Öykü Özen (Auteur), Hüseyin Buğra Özgün (Auteur), Sami Ağuş (Auteur), Cihan Civan Civaş (Auteur), Deniz Atasoy (Auteur), Bayram Yılmaz (Auteur)
• Format: Livre
• Publié: Elsevier, 2024-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Objective: The prevalence of obesity has increased over the past three decades. Proopiomelanocortin (POMC) neurons in the hypothalamic arcuate nucleus (ARC) play a vital role in induction of satiety. Chronic consumption of high-fat diet is known to reduce hypothalamic neuronal sensitivity to hormone...