Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers

• Asıl Yazarlar: James O. McNamara (Yazar), Aloysius J. Klingelhutz (Yazar), Luiza I. Hernandez (Yazar), Frank J. Hernandez (Yazar), Katie S. Flenker (Yazar), Paloma H. Giangrande (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2013-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Recent clinical trials of small interfering RNAs (siRNAs) highlight the need for robust delivery technologies that will facilitate the successful application of these therapeutics to humans. Arguably, cell targeting by conjugation to cell-specific ligands provides a viable solution to this problem....