Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers

• Κύριοι συγγραφείς: James O. McNamara (Συγγραφέας), Aloysius J. Klingelhutz (Συγγραφέας), Luiza I. Hernandez (Συγγραφέας), Frank J. Hernandez (Συγγραφέας), Katie S. Flenker (Συγγραφέας), Paloma H. Giangrande (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2013-03-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Recent clinical trials of small interfering RNAs (siRNAs) highlight the need for robust delivery technologies that will facilitate the successful application of these therapeutics to humans. Arguably, cell targeting by conjugation to cell-specific ligands provides a viable solution to this problem....