Correlations among the plasma concentrations of first-line anti-tuberculosis drugs and the physiological parameters influencing concentrations

• Главные авторы: Lin Cheng (Автор), Ming Luo (Автор), Yan Guo (Автор), Yunfan Fan (Автор), Pengsen Wang (Автор), Gang Zhou (Автор), Shiwei Qin (Автор), Bangbi Weng (Автор), Peibo Li (Автор), Zhirui Liu (Автор), Songtao Liu (Автор)
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• Опубликовано: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Предметы: article
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Background: The plasma concentrations of the four most commonly used first-line anti-tuberculosis (TB) drugs, isoniazid (INH), rifampicin (RMP), ethambutol (EMB), and pyrazinamide (PZA), are often not within the therapeutic range. Insufficient drug exposure could lead to drug resistance and treatmen...