XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression

• Auteurs principaux: Wei-Qiang Yang (Auteur), Wei-Jun Zhao (Auteur), Liu-Lian Zhu (Auteur), Shuai-Jun Xu (Auteur), Xue-Lin Zhang (Auteur), Yong Liang (Auteur), Xiao-Fei Ding (Auteur), Alexander Kiselyov (Auteur), Guang Chen (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Doublecortin-like kinase 1 (DCLK1) is a cancer stem cell marker that is highly expressed in various types of human cancer, and a protein kinase target for cancer therapy that is attracting increasing interest. However, no drug candidates targeting DCLK1 kinase have been developed in clinical trials...