XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression

• Main Authors: Wei-Qiang Yang (Author), Wei-Jun Zhao (Author), Liu-Lian Zhu (Author), Shuai-Jun Xu (Author), Xue-Lin Zhang (Author), Yong Liang (Author), Xiao-Fei Ding (Author), Alexander Kiselyov (Author), Guang Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Doublecortin-like kinase 1 (DCLK1) is a cancer stem cell marker that is highly expressed in various types of human cancer, and a protein kinase target for cancer therapy that is attracting increasing interest. However, no drug candidates targeting DCLK1 kinase have been developed in clinical trials...