Aminooxyacetic acid hemihydrochloride inhibits osteoclast differentiation and bone resorption by attenuating oxidative phosphorylation

• 主要な著者: Biao Yang (著者), Yuangang Su (著者), Shuai Han (著者), Runfeng Chen (著者), Ran Sun (著者), Kewei Rong (著者), Feng Long (著者), Hailong Teng (著者), Jinmin Zhao (著者), Qian Liu (著者), An Qin (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Osteoclasts undergo active metabolic reprogramming to acquire the energy needed during differentiation and bone resorption. Compared with immature osteoclasts, mature osteoclasts comprise higher levels of electron transport chain enzymes and more metabolically active mitochondria. Of all energy meta...